CLINICAL AND LABORATORY FEATURES OFNEPHROPATHY IN CHILDREN WITH DIABETES MELLITUS

Abstract

Diabetes currently occupies a leading position in pediatric endocrinology with diseases, disorders and complications that can lead to a decrease in life expectancy. According to the World Health Organization, the incidence of diabetes in the world doubles every 10-15 years, and the life expectancy of patients is lower than among the general population. As a result of type 1 diabetes, the patient’s ability to work and their life are impaired, which indicates that the disease is an important medical, social and economic problem in modern society. Materials and research methods. 50 patients with type 1 diabetes mellitus aged 6 to 16 years, 28 boys and 22 girls. The control group consisted of 20 patients with type 1 diabetes mellitus who did not have hyperuricemia, hyperuricosis, protienuria, that is, normal urinalysis. ... Research results. The data obtained confirm that hyperuricemia, hyperuricosuria and urate nephropathy are common in children with diabetes. The onset of the disease is less pronounced, the course is relatively positive. However, if the diagnosis is not made at an early stage, that is, without dietary correction of purine metabolism, the process can become chronic (interstitial nephritis, DN, microbial inflammatory process of the kidneys, chronic renal failure can be observed). Conclusion: Given the type of disease, dysmetabolic changes are difficult to reverse, but we can conclude that dietary medico-time adjustments can be avoided in a timely manner.