CLINICAL AND LABORATORY PARAMETERS OF LIVER FUNCTION IN CHRONIC KIDNEY DISEASE AND THEIR CORRECTION

Abstract

Chronic kidney disease (CKD) is a global healthcare problem due to its high economic burden and its contribution to the increasing prevalence of cardiovascular diseases. The often asymptomatic course of CKD leads to the extrapolation of the prevalence of end-stage renal disease to the overall prevalence of CKD. To assess the global prevalence of this condition, the authors conducted a literature search in the PubMed, Scopus, and eLibrary databases. A total of 32 sources were analyzed, covering various aspects of the topic.
The review demonstrates the high relevance and social significance of CKD worldwide due to its high prevalence (ranging from 6.86% to 34.3% across different countries), low detection rates at early stages, significant comorbidity, and challenges in implementing preventive measures. Determining the current prevalence of CKD is essential for the proper allocation of healthcare resources in prevention, early diagnosis, and treatment.