PHARMACOKINETICS OF ANTIBIOTICS IN EXPERIMENTAL GUNSHOT WOUNDS

Authors

  • GULOMIDIN MINKHODZHIEVICH HODJIMATOV Professor of the Department of General Surgery of the Faculty of Professional Development and Training of Doctors of Andijan State Medical Institute
  • KAMAL KARIMOVICH MIRZAEV Associate professor of the Department of General Surgery of the Faculty of Professional Development and Registration of Doctors of Andijan State Medical Institute
  • DILSHOD TURDALIYEVICH AZIZOV Assistant Professor, Department of General Surgery, Andijan State Medical Institute

Keywords:

gunshot wound, lymphatic antibiotic therapy, antibiotics pharmacokinetics

Abstract

Experimental studies on the pharmacokinetics of gentamicin were performed on 40 rabbits with various methods of injection after the infliction of gunshot wounds on extremities. The results showed that the method of lymphotropic antibiotic therapy provides a more stable and long-term saturation of blood. The highest and the longest retaining concentration of gentamicin in the lymph nodes and soft tissue of gunshot wounds is reached at lymphotropic method of injection.

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Published

2021-02-15

Issue

Vol. 7 No. 02 (2021): journalnx.

Section

Articles

License

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

How to Cite

PHARMACOKINETICS OF ANTIBIOTICS IN EXPERIMENTAL GUNSHOT WOUNDS. (2021). JournalNX - A Multidisciplinary Peer Reviewed Journal, 7(02), 120-123. https://repo.journalnx.com/index.php/nx/article/view/1765